kromosoomi esinemisest tingitud kaasasündinud sündroom, millele on iseloomulikud vaimne alaareng, holopros­entse­faalia, kükloopia, suulae- ja huulelõhe, polü­dak­tüülia ning südame, seedeelundite ja , a chromosomal disorder resulting in a syndrome characterized by specific (midline) dysmorphic features and organ malformations, a congenital condition that is characterized especially by usually severe mental retardation and by craniofacial, cardiac, ocular, and cerebral abnormalities, is caused by trisomy of the human chromos