erilised liidused, mis ühendavad epiteelirakke basaalse laaminaga ja alloleva rakuvälise maatriksiga
Hemidesmosomes (HD) are very small stud- or rivet-like structures on the inner basal surface of keratinocytes in the epidermis of skin. They are similar in form to desmosomes when visualized by electron microscopy. While desmosomes link two cells together, hemidesmosomes attach one cell to the extracellular matrix. Instead of desmogleins, hemidesmosomes use integrins.Hemidesmosomes are asymmetrical and are found in epithelial cells connecting the basal face of the cell to basal lamina.
Hea teada
Hemidesmosoomid muudavad epiteelkoe ühtseks tervikuks ja annavad talle tugevuse, kuivõrd nad loovad kaudse ühenduse keratiini sisaldava raku tsütoskeleti ja rakuvälise maatriksi valkude vahel.